site directed mutagenesis การใช้

• Site directed mutagenesis and deletion analysis have shown that the TIR domain is essential for Toll and IL-1R activities.
• A variation of this method, called SPRINP, prevents this artifact and has been used in different types of site directed mutagenesis.
• The first reported glycosynthase was a mutant of the Agrobacterium sp . ?-glucosidase / galactosidase in which the nucleophile glutamate 358 was mutated to an alanine by site directed mutagenesis.